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Similar to the blood/subcutaneous tissue comparison, no major differences in the pulse parameters frequency, amplitude, and height between the blood and the brain were found as indicated by the absence of significant main and post hoc effects (Supplemental Tables 1 and 3).
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Surprisingly, bacteria were found as early as 30 minutes in vital organs such as the brain and heart.
Primary cilia in the brain are found in glia as well.
Glutamate is the primary excitatory neurotransmitter in the brain and is found as a neurotransmitter in approximately 60% of brain neurons, including almost all cortical pyramidal neurons.
Hypoxic brain injury has been found as a primary cause of death in up to 10% of severe burn patients in an age-dependent manner [ 6].
In a murine model of pneumococcal meningitis, better clinical outcome and decreased brain inflammation in Nlrp3−/− (and Asc−/−) mice was found as compared to WT controls [ 18].
No brain metastases were found in these animals; as breast tumor FC-IBC02 xenografts grew quickly and the mice had to be killed, there was probably not enough time for the development of spontaneous brain metastasis in the orthotopic xenograft models.
As mentioned in the introduction, many brain modules were found to be highly preserved across the three brain regions, which is why they received the same color label.
1,4-Dihydropyridines were thoroughly investigated as carriers for specific drug delivery to the brain and were found very efficient.
For procedural memory, activations were found in motor as well as in non-motor brain areas.
However, endothelial dysfunction and blood brain barrier (BBB) failure were found responsible as a mechanism of injury [3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com