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The easy trans-BBB migration of developed formulations through endocytosis, and inhibition of P-gp efflux pump present in brain were established by Pluronic F-68 and/or polysorbate 80 (Tween 80/Tw).
Metastatic tumors to the brain were established by direct injection into the striatum or by intracarotid injection of B16F10 mouse melanoma cells in C57Bl mice.
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BBB in larval brain is established by surface glia, which are distinct from cortex glia [ 27, 28].
hNSC lines 1 and 2 were established by fetal human brain as described [1]; at passage 14 and 16 respectively, they were shifted to appropriate oxygen culture conditions.
The mechanisms by which sex differences in the brain are established and controlled during development are not understood in detail, but sex hormones clearly play major roles.
TH4-7-5 cestablishedstabyished by HIV-1 infectiof of the human glioma cell line 85HG-66 derived from astrocytoma brain tumors (Brack-Werner et al. 1992).
Lesion profiles were established by following the standard method of Fraser and Dickinson (13 ) and using 6 brains per isolate.
Lesion profiles of the brains were established according to the standard method described by Fraser and Dickinson (34 ).
Such a "brain" can be established by a proper design of a technological database and its database management system (DBMS).
A rat model of chronic brain damage was established by chronic intragastric administration of aluminium gluconate (Al3+ 200 mg/kg per day, 5d a week for 20 weeks).
In many countries strict criteria for diagnosis of brain death have been established by common consent among medical, religious, ethical, and legal experts.
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