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Skin and fetal brain were enriched with 'IN' component, consistent with a larger proportion of ligand-receptor interactions in these tissues.
Overall, the thalamic, hippocampal, and cortical areas of the brain were enriched with asymmetrical (containing chiral carbons) polyunsaturated species such as CLs of m/ z 1475.996, 1497.980, and 1499.996 in addition to the symmetrical tetralinoleoyl-CL (m/ z 1447.964).
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For example, glioblastoma tumor cell-secreted exosomes in the brain are enriched with angiogenic proteins and can be taken up by brain microvascular endothelial cells to stimulate tubal formation [ 4].
This idea was first proposed by Flores et al. (2008) who showed that stem cell compartments from hair follicles, intestine, testis, cornea and brain are enriched with cells with the longest telomeres.
Moreover, it was observed that extracellular vesicles derived from hypoxic brain tumour glioblastoma multiform cells were enriched with angiogenic stimulatory molecules, such as IL-8 and PDGF [ 67].
The resulting peptides were enriched with StageTips.
If the abundance of MLE and MSL-2 is indicative of the level of DCC binding and dosage compensation in a tissue (Dahlsveen et al. 2006), then one would expect the brain to be enriched with genes that overshoot the expected 2-fold upregulation.
The ChIP experiments were performed using the extract isolated from dissected brat mutant brains that are enriched with type II neuroblasts.
Accordingly, Khare et al. [ 68] have shown with tiling arrays that in mouse and the human brain, exon intron boundaries are enriched with 5-hmC and that constitutive exons show a distinct 5-hmC pattern different from that of alternatively spliced exons.
We show here that some regions on specific chromosomes are enriched with brain-enriched gene expression.
Of note, Aβ plaques deposited in the AD brain are found to be enriched with metals, and in particular copper [11], [12].
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