The brain weight was also greater in HSD than in FTLD-U HS.
Whereas brain weight was also affected (−14.6%), the thickness of selective brain layers such as the hippocampal CA1 pyramidal layer, the granular cell layer of the dentate gyrus and the neurogenic subventricular zone (SVZ) were more dramatically decreased (−40, −22 and −26%, respectively).
For example, Silver did not find any difference in organic osmolytes, myoinositol, taurine, glutamate, glutamine, aspartate, alanine and glycine between uraemic nondialysed mice and nonuraemic controls using a mouse model, although significant decreases in brain water, measured by weight, were also observed in uraemic nondialysed mice when compared with normal control animals at 42 hours [ 47].
However, this signal was only observed with one of our two validated anti-G72 antibodies and a signal at the same apparent molecular weight was also detected in brain lysates from rat, which does not have a G72 gene, thus making it highly unlikely that this band represents G72.
The weight is also an issue.
Placenta weight was also reduced (Table 1).
Body weight was also monitored.
Tumor weight was also recorded.
These beta weights were also subsequently used to assess potential relationships between brain activity and behavioral measures/group characteristics.
Adult organ weights were also reduced in size largely in proportion to total body weight, except the brain which was relatively larger in the mutants (Fig. 4b,c).
