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The highest activity in the brain was seen in the striatum and insula areas containing a high density of dopamine D1/D2 and D1 receptors, respectively.
Under the "other tumors" category in Table 2, one metastatic finding in the calvarium was seen in a patient with ocular adenoid cystic cancer and one metastatic finding in the brain was seen in a patient with ileum cancer.
The highest radioactivity in the brain was seen in the insula (AUC0-t = 586.0 ± 14.8%ID/g × min) and striatum (AUC0-t = 582.0 ± 5.9%ID/g × min), but high amounts were also observed in other cortical regions.
However, two other lesions observed in the present case were not observed in the 141-day-old calf but were seen in other bovine JE cases: pulmonary emphysema was observed in a 24-month-old milking cow in 1950, and congestion of the brain was seen in an 18-month-old Japanese Black cow in 1996 [ 7, 9].
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Expression levels equal to those in whole brain were seen in frontal cortex and for hGPR17-L in hippocampus, whereas lower levels were present in all other brain tissues for both isoforms in varying degrees.
The first, most evident defect observed in clonal loss-of-function experiments was the reduction in cell number of the ALl1 lineage; only 20% of the cells present in the wild-type adult brain were seen in the mutant condition.
Over the 6 h studied, a time-dependent reduction in Act D brain concentration was seen in WT mice, whereas Act D levels in the brain of Abcb1a/1b−/− mice were maintained.
In addition, brain activity was seen in the calcarine gyrus, and the cerebellum.
The most consistent relationship between exposure variables and brain volume was seen in the thalamus and caudate.
Traumatic brain injury was seen in six patients in the hyponatraemic group, while none was found in the normonatraemic group (table 2).
Perhaps the most consistent relationship between exposure variables and brain volume was seen in the caudate and, less so, in the putamen [ 34].
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