Sentence examples for brain transcriptome and behavior from inspiring English sources

The current study was designed to investigate the transgenerational actions of vinclozolin on the brain transcriptome and behavior.

The combined current observations indicate that vinclozolin exposure of a gestating female rat during gonadal sex determination can promote a transgenerational alteration in the brain transcriptome and behavior.

The current observations demonstrate that the exposure of a gestating female during gonadal sex determination to the environmental compound vinclozolin can promote a transgenerational effect on the brain, three generations removed from the exposure, involving alterations in the brain transcriptome and behavior.

Sex-specific effects were observed in both the male and female brain transcriptome and behavior correlations.

These observations demonstrate that an embryonic exposure to an environmental compound appears to promote a reprogramming of brain development that correlates with transgenerational sex-specific alterations in the brain transcriptomes and behavior.

Due to this effect on behavior, the current study extends this analysis to investigate the transgenerational effects of vinclozolin on the brain transcriptome and anxiety-like behavior.

Although correlation of pathways or genes with specified brain functions cannot be made, observations suggest transgenerational reprogramming of the brain transcriptome may alter behavior.

The role of epigenetic alterations in the brain cell populations as a causal factor in the transcriptome and behavior alterations remains to be elucidated in future studies.

These molecular changes in the brain transcriptome are associated with altered behavior, but the causal relationships remain to be established.

Although anxiety behaviors were the focus, the whole brain transcriptome data suggests other behavioral indices may also be influenced.

Furthermore, variants will be mapped against a list of brain-expressed genes determined by expression array analysis across 57 postmortem brains and multiple brain regions in a recent study of the human brain transcriptome throughout development and adulthood [ 49].