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All others sheep brain tissues were from Italian field cases detected by active and passive surveillance and characterised by discriminatory western blotting for molecular strain typing and by complete sequencing of the PRNP open reading frame, according to published protocols [49], [50].
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Brain tissue was from homozygous APPV717F transgenic male mice.
Human brain tissues were obtained from patients who suffered from stroke and age-matched controls for this study.
Human brain tissues were obtained from anonymized autopsy patients from files of the Institute of Neuropathology at the University Medical Center Hamburg-Eppendorf Hamburg-Eppendorf and National Taiwan University Hospitalhe Nasionapprovedn University Hospital ethics committee.
SNPs from the liver were tested for enrichments using the HepG2 annotations and SNPs from the three brain tissues were tested from regulatory annotations in the 7 brain tissues.
Tissue samples from human glioma and normal brain tissues were obtained from the Brain Institute, Qingdao Medical University Associate Hospital (Qingdao, China).
Fresh frozen brain tissues from multiple sclerosis patients and control brain tissues were obtained from the Rocky Mountain Brain Bank.
Normal human brain tissues were purchased from Clontech laboratories (Mountain View, CA); the tissues were isolated from 8 male Caucasians (ages 43-65).
Brain tissues were collected from light-pulsed rats and compared to brain tissue samples obtained from control animals in darkness at ZT 15.
Brain tissues were received from the NIH NeuroBioBank at the University of Maryland and University of Pittsburgh.
In the present study brain tissues were prepared from patients with patients DNTC, calcified and non-calcified Alzheimer's disease (AD) patients.
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