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A hyper-viscoelastic material model is developed to better represent the mechanical response of the brain tissue over a large strain/high frequency range applicable for blast scenarios.
For CED to be effectively translated to clinical trials, it will be necessary to use flow rates within this range for therapeutic agents to be distributed through clinically relevant volumes of brain tissue over a time period which is acceptable to patients [ 31].
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Andreasen et al. found that the duration of relapse was closely related to loss of brain tissue over time in multiple brain regions, including total cerebral volume loss, as well as loss in subregions, particularly the frontal lobes.
According to 5-hmC signal quantification, the intensity of 5-hmC stainingraduallyly decreased in brain tissue over time and fell dramatically in embryonic tongue between 12.5 dpc and 15.5 dpc.
Brain tissue-specific ECM (bECM) was extracted from decellularized rat brain tissue using a protocol previously described (see Methods)12.
(a) The decellularization protocol (see Methods) removed ~99.2% of the DNA content from the brain tissue versus a whole brain.
CTE is currently diagnosed through examining a patient's brain tissue under a microscope.
Dr. Zimmerman extracted brain tissue from a patient who had died from the disease.
Slice preparation from human brain tissue followed a procedure that was developed in our lab34,35,36,37,58,59.
Scientists already knew that CSF plays an important role cleansing brain tissue, carrying away waste products and carrying nutrients to brain tissue through a process known as diffusion.
A car accident can smash a head, stretching and tearing brain tissue across a wide area.
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