Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
To determine, if the transcriptional profiles associated with primed microglia are preserved in mouse brain tissue, expression sets of App-Ps1, aged, rTg4510 and ME7 prion infected mice (-/+ LPS) were analyzed.
Similar(59)
Transcriptional profiles of microglia isolated from four mouse models of aging and disease and four brain tissue expression data sets were analyzed in parallel and compared using WGCNA [ 17].
The networks we infer from other brain tissue data sets showed comparable topologies.
Conserved synteny regions of PK genes with similar overall expression levels and low expression in the brain tissue were used as a background set.
Next, the effect of specificity of the brain tissue region on SNCA expression was assessed.
(B) Heatmaps of multi-tissue expression data set (n = 1,042).
Expression in brain tissue was low.
We selected 'testis' as tissue focus and chose 'brain' as interfering tissue, as it has been shown that various CT genes also exhibit expression in brain tissue (13).
Otherwise, analysis of brain tissue extracts showed a decrease of SphK1 expression in AD brains whereas SPL expression was increased.
Immunoblotting data were presented as relative expression, using normal brain tissue values as 100%.
In addition, we compared these expression levels to brain tissue as shown in Figure 1D.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com