Sentence examples for brain tissue and cell from inspiring English sources
The positive experimental results obtained only in the brain tissue and cell line indicated that the A-to-I RNA editing event that occurred at site chr4_+_ 57021835 was brain-specific.
Our goal was to establish a methodology which enabled sequencing from brain tissue, and cell cultured samples without the use of specific viral enhancement, ultracentrifugation or filtration to identify novel viruses, or obtain genome sequence for known virus species.
It has been shown recently that α2δ-1 and PrP can co-immunoprecipitate from both brain tissue and cell lines [ 35], and that the interaction between pathogenic mutant PrP and α2δ-1 results in the intracellular retention of both species [ 35].
In fact, the inclusions easily observed in HD brain tissue and cell models tend to be about 5 μm in diameter, corresponding roughly to an HTT exon1 content of 10 molecules, and this allows for a huge range of smaller aggregate sizes that will presumably be more difficult to detect in cells or cell extracts.
For example, mouse-derived brain tissue and cell lines have been used in conjunction with AP-MS in the characterization of the interactome of LDL receptor-related protein-1 (LRP-1), a recently identified phagocytic receptor for myelin debris in the central nervous system [ 56].
Data on nanoparticle effects in the brain tissue and cells both in vitro and in vivo are scarce and two main features were observed, namely, nanoparticle-mediated oxidative stress and inflammatory response [ 19– 23].
Protein samples of brain tissues and cell lysate were mixed with 5 × SDS-PAGE Sample Buffer (Genstar, China) and boiled for 10 min.
Numerous studies have found meQTLs in blood leukocytes, buccal cells, brain tissue, and lymphoblast cell lines [ 3- 7], though there is only modest overlap between the SNP-CpG relationships identified in each study.
In chronic, established infection, HIV DNA has been recovered from homogenized brain tissue and specific cell types in the CNS including macrophages, microglia, and astrocytes, supporting the concept of anatomic and cellular reservoirs for HIV within the CNS [ 39– 42].
Nevertheless, breast tissue and breast epithelial cells (MCF10a) had significantly higher mtDNA copy number than brain tissue and fibroblast cells, which highlights the differences between terminally differentiated cell types.
Recently, HLA-Gpos Treg cells were identified in MS cerebrospinal fluid, as well as in inflammatory brain tissue, and these cells are thought to function as suppressor cells, counterbalancing the tissue destructive effects of autoimmune inflammation [37].
