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We now show that the short variants are, similarly to Carp, up-regulated by BDNF treatment in the rat hippocampus, and that in human these variants are expressed in brain structures relevant to cognition.
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Alzheimer disease (AD) is a fatal dementia with progressive accumulation of protein aggregates composed of amyloid-beta (Aβ) and the microtubule-associated Tau protein in brain structures relevant for learning and memory [ 1].
Hemispheric comparison of the sizes of brain structures, relevant for language processing, revealed comparable anatomical asymmetries between humans and great apes in the Planum temporale, the Sylvian fissure and the Broca or homolog areas [ 10- 17].
Holloway, R. Does allometry mask important brain structure residuals relevant to species-specific behavioural evolution?
In aging humans, it has been demonstrated that regular aerobic exercise improves the regional cerebral blood flow (rCBF) in various relevant brain structures in response to cognitive tasks along with better task performance [ 7].
Which of the brain structures identified to contribute to performance monitoring are relevant for the awareness that an error has been made?
Current deep brain stimulation paradigms deliver continuous stimulation to deep brain structures to ameliorate the symptoms of Parkinson's disease.
This underlines the effect of maintaining sobriety on the recovery of different brain structures and fits to our results, although there are relevant methodological differences between the studies.
Our findings suggest that individual differences in cognitive style pertaining to empathizing or systemizing abilities could be explained by differences in the volume of brain structures that are functionally relevant to empathizing and systemizing.
These span limbic, sensorimotor, and midline brain structures, and may be relevant to the clinical effectiveness of mirtazapine.
The study revealed brain structures surprisingly similar to our own.
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