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Lenroot and Giedd (26) caution that relationships between brain structures and cognition are rarely straightforward even in healthy youth.
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A different but also rapidly growing research direction deals with the use of connectivity measures to link brain structure and cognition.
The majority of studies examining the relationship between age-related changes in brain structure and cognition focus on grey matter (GM).
Longitudinal evidence linking diabetic retinopathy with changes in brain structure and cognition is sparse.
Specifically, animal studies have shown that hyperglycemia but not hypoglycemia affects brain structure and cognition (5).
Here we investigated how lean and overweight/obese (o/o) adults differed in their food choices and how brain structure and cognition may be associated with those choices.
While research has started to consider the direct effect of individual CVD risk factors on brain structure, little is known about how such factors modulate or contribute to the effect of education on brain structure and cognition.
In contrast to investigations into the association between glycemia and cognition, fewer studies have explored the possible links between insulin levels and IR, and brain structure and cognitive performance.
Several factors might have contributed to the dissociation between the treatment effects on brain structure and on cognition (Launer et al. [ 14] found no treatment effects on cognition).
It is now generally agreed that there are inherent sex differences in healthy individuals across a number of neurobiological domains (including brain structure, neurochemistry, and cognition).
The identified multimodal biomarkers could predict not only disease status but also cognitive function to help elucidate the biological pathway from gene to brain structure and function, and to cognition and disease.
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