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Most studies have examined the effects of estrogens on primary neurons or brain slices derived from animals.
Although brain slices derived from sham and SAR 2 W/kg exposed animals showed a generally weakened LTD effect compared to the cage controls, both conditions did not differ in their slope response values (psham vs. 2 W/kg = 0.06).
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Brains slices derived from APP/PS1 mice showed significantly impaired long-term potentiation (LTP), and RanBP9 reduction significantly enhanced paired pulse facilitation and LTP, as well as partially rescued contextual memory deficits associated with APP/PS1 mice.
In order to automate the brain tumor (Glioblastoma) detection, we proposed a novel approach of skull stripping for axial slices derived from MRI.
For patch clamp recordings standard procedures were also used to prepare 300 µM thick horizontal slices derived from juvenile mice (P18 28) (mEPSCs, mIPSCs) or coronal slices derived from adult mice for LTP experiments.
For extracellular recordings hemisected horizontal slices derived from adult mice or coronal slices (400 µm) derived from juvenile and adult mice were prepared with a vibroslicer (Campden Instruments, Silbey, UK).
To confirm these findings in a neuroectodermal tissue we subsequently employed human hippocampal brain slice cultures (OHSCs) derived from epilepsy surgery (four individuals, Fig. 6A D).
A human brain network derived from coma-causing brainstem lesions.
Investigating the Role of Brain Stem in Alzheimer's Disease using Directional Brain Networks derived from Resting State fMRI.
Mini brain: An organoid derived from stem cells contains different brain regions.
Organotypic slice culture derived from postnatal brain and matured in vitro, is a widely used model for the study of neurodegenerative mechanisms and potential therapeutics.
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