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But this is no simple brain-siege.
Styron remembers his brain feeling "under siege", while his thoughts were repeatedly "engulfed by a toxic and unnameable tide".
From time to time, Dr. Knowles, a trim 39-year-old man with an engaging manner, points over one shoulder and refers to it -- which, in fact, is a magnified image of human brain tissue under siege from Alzheimer's disease.
"We need a siege mentality.
"The siege mentality again".
There is an air of siege mentality.
He wants a siege mentality.
Add in impossible-to-avoid news media continuously scaring us in their attempt to capture market share and you have a brain convinced its living in a state of siege.
"We are under siege.
The siege begins.
Baghdad under siege.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com