Sentence examples for brain sequestration from inspiring English sources

HUVEC expresses ICAM-1 on TNF stimulation but not CD36 and is used widely as a model of brain sequestration in vitro [21], [36], [59], [89].

They had the means (GrB+ and cytotoxic) and opportunity (brain sequestration 7 days p.i). to be responsible for the neuropathology seen during PbA infection.

This finding was explained by the fact that there is a progressive decline in plasma Ab42 as Alzheimer disease progresses, indicating increased brain sequestration of β-amyloid.

Whenever brain and retinal histology has been compared in cases of fatal paediatric cerebral malaria, brain sequestration is always associated with retinal sequestration (Lewallen et al., 2000; White et al., 2009).

Diseased brains show a phenotype of iron deficiency in the presence of increased brain iron, suggesting sequestration of iron in biologically unavailable complexes [32].

When I read about sequestration, my brain seizes.

Binding to the endothelial receptor ICAM-1 has been associated with sequestration in brain vasculature [5] and showed a weak but not statistically significant association in one study with cerebral malaria (CM), while adhesion to CD36 showed no association [6].

Alternatively, the inflammation associated with the sites of parasitized and non-parasitized red blood cells sequestration and brain ischemia could lead to neuronal damage and exposure of self-antigens which in turn will elicit a self-reactive antibody response, thus amplifying brain damage [18] [22].

This biological context suggests inference of several distinct pathological processes from the retina to the brain is plausible, including sequestration, haemorrhage, blood-tissue barrier breakdown, and ischaemia (MacCormick et al., 2014).

As suggested by three complementary theories developed over the past century, CM might be a likely consequence of several concomitant phenomena, including iRBC sequestration in brain microvessels, enhanced BBB permeability, and release of pro-inflammatory molecules from host immune cells.

Again in a post-mortem study, Silamut et al. [ 4] observed, generalised endothelial activation, not confined to sites of parasite sequestration in brain samples from Thai and Vietnamese adults who died from severe malaria, further supporting the possibility of endothelial activation occurring independently of IE binding [ 4].