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One in 2009, for example, found that brain samples from people who died of Alzheimer's or Lou Gehrig's disease had BMAA levels as high as 256 ng/mg.
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The study's researchers compared brain samples from 10 people who had Alzheimer's with 10 people who did not.
They applied antibodies--designed to tag garbled versions of ubiquitin and bAPP--to brain samples from Alzheimer's patients and people with Down syndrome, who develop early symptoms of Alzheimer's.
After conducting maze tests, the neuroscientist Fred H. Gage and his colleagues examined brain samples from the mice.
Dr. Weinberger has tested this idea by analyzing the activity of the gene in a large collection of brain samples from schizophrenic patients.
A 2013 study compared brain samples from mentally healthy organ donors with samples from donors who were clinically depressed at the time of their deaths.
By studying post-mortem brain samples (from those who were subjected to severe verbal and emotional abuse as children), the researchers discovered abnormalities in the amygdala an area of the brain that serves as an emotional thermostat.
Brain samples from C57 BL/6 mice were isolated from anesthetized and perfused animals[63].
The team could also identify dying brain cells in blood samples from people who had brain damage due to head trauma or cardiac arrest.
In the second case, news reports said a department veterinarian had started to take a brain sample from a staggering cow he thought had brain disease, but was overruled by a regional officer.
A team led by neurologist Carlos Pardo and his postdoc, Diana Vargos, at Johns Hopkins School of Medicine and colleagues has now looked at tissue from the brains of seven people with autism, aged 5 to 44 years, and seven brain autopsy samples from nonautistic people.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com