After conducting maze tests, the neuroscientist Fred H. Gage and his colleagues examined brain samples from the mice.
Their study involved looking at large, intact brain samples from mice, as well as monitoring live mouse brains.
Dr. Weinberger has tested this idea by analyzing the activity of the gene in a large collection of brain samples from schizophrenic patients.
Brain samples from Alzheimer's patients were 24 percent more active in killing the bacteria.
Because brain samples from the affected individuals described by Simpson et al. were not available for analysis of brain gangliosides and pathology, mice deficient in ganglioside glycosyltransferases are important for gaining insight into the potential mechanisms underlying this disorder.
A challenge experiment with NNV was performed with Atlantic cod juveniles and brain samples from virus infected and uninfected fish were used for microarray analysis.
Accordingly, HSV-1 DNA has been detected in brain samples from AD patients by PCR in different central nervous system (CNS) regions, including the frontal lobe, the temporal lobe and the hippocampus16,17,18,19.
These findings advocate for the necessity to profile the expression of the dystrophin isoforms in post-mortem brain samples from people with dystrophinopathies in order to elucidate the transcriptional mechanisms underlying the behavioural and learning problems in DMD.
Moreau, M. P., Bruse, S. E., David-Rus, R., Buyske, S. & Brzustowicz, L. M. Altered microRNA expression profiles in postmortem brain samples from individuals with schizophrenia and bipolar disorder.
To see if a prominent B-cell presence in the brain might be a common occurrence in old age even among healthy people, they looked at brain samples from nine age-matched patients with no history of stroke or dementia.
