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We used frozen brain samples from a total of 17 non-demented control subjects and 37 pathologically confirmed subjects with Alzheimer's disease (males/females: control subjects, 10/7; subjects with Alzheimer's disease, 20/17), provided by the Institute for Brain Aging and the Dementia and Alzheimer's Disease Research Center at the University of California, Irvine.
We also re-used brain samples from a passive immunization study.
A subset of the validated genes was then assessed in brain samples from a separate cohort of subjects.
Therefore we examined brain samples from a previously published anti-Aβ immunotherapy study for changes in the inflammatory state.
Normal pediatric brain samples from a variety of anatomic sites were obtained during routine epilepsy surgery or autopsy at Children's Hospital Colorado.
Brain specimens from one 6-week-old goose, which died during the encephalitis outbreak in a Hungarian goose flock, and brain samples from a goshawk, which also died from encephalitis, were used for WNV nucleic acid determination.
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HCV RNA positive- and negative-strand copy numbers were determined in brain samples from all patients by a strand-specific reverse transcriptase with subsequent PCR amplification and interpreted from a standard curve.
We performed Western blot analysis on extracts of homogenates prepared from brain samples from all 3 VPSPr patients.
Test results of brain samples from all animals were positive for macaque-adapted BSE by Western blot analysis.
In the second case, news reports said a department veterinarian had started to take a brain sample from a staggering cow he thought had brain disease, but was overruled by a regional officer.
In August 2004, a brain sample from a suspected rabid mongoose was submitted to the Allerton Veterinary Institute in Pietermaritzburg, KwaZulu-Natal, South Africa.
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