Sentence examples for brain samples derived from from inspiring English sources
For comparison purposes, we used 5 brain samples derived from non-infected age- and sex-matched control macaques.
To achieve that, genes identified as involved with neuronal differentiation exclusively in schizophrenia were analyzed by co-expression network in post-mortem brain samples derived from adult patients and controls.
A role for specific miRNAs in the development of common neurodegenerative diseases has further been suggested by comparing changes in miRNA expression profiles in brain samples derived from patients and controls (32, 34).
p53 expression is elevated in damaged neurons in acute models of injury such as ischemia and epilepsy and in brain tissue samples derived from patients with chronic neurodegenerative diseases, which is consistent with data showing that the absence of p53 protects neurons from a wide variety of acute toxic insults [33].
Moreover, comparative analysis of samples derived from different brain regions produced an increased molecular resolution for our analysis.
Using a panel of DNA samples derived from various brain regions (parietal lobe, occipital lobe, cerebellum, frontal cortex, temporal gyrus, hippocampus and vermis) we confirm the unmethylated status of the promoter of KCNK9, which agrees with the observations obtained from WGBS (data not shown).
This in turn is reflected by the more non-neuronally specific transcriptome patterns seen in samples derived from the total brain in this study.
Tissue samples derived from anatomically different brain regions, even when carefully dissected, show substantial complexity at a cellular level (28).
During this screen, we identified a region overlapping the nc886 transcript that was consistently partially methylated in DNA samples derived from leukocytes, liver, brain and placenta tissues.
In addition to AD correlations we found high scoring correlations with samples derived from Huntington's disease (HD), Down's syndrome (DS), Parkinson's disease (PD) and bipolar disorder (BD) brains.
