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Histone deacetylases (HDACs) belong to a family of proteins that by catalyzing the deacetylation of histones plays an important role in the epigenetic brain regulation of transcription, apoptosis as well as learning and memory [53], [54].
The increased plasma endocannabinoid levels could influence liver, muscle, and brain regulation of glucose homeostasis (21).
This shows that, in the brain, regulation of phosphoinositide levels by the SYNJ1 5′-phosphatase domain is essential for proper vesicle trafficking and coating/uncoating of endocytic vesicles [ 11, 34].
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For example, enkephalin neuropeptides function as neurotransmitters in the brain for regulation of behavior and pain and are also involved in peripheral actions including regulation of intestinal motility and immune cell functions (1, 2).
Taken in high enough doses, heroin and other opioids suppress the brain's regulation of breathing and other life-sustaining functions.
These genetic variations affect the brain's regulation of dopamine, the neurotransmitter associated with the processing of rewards and new stimuli (and drugs like cocaine).
This chapter considers the process of adult neurogenesis in the mammalian brain, its regulation by neuroendocrine and experiential factors, and the likely function of adult-generated neurons.
The team applies multiple techniques in studying the role of the neuropeptide orexin in the brain's regulation of eating behaviors and energy expenditure in rodents.
The present study was designed to examine the beneficial effects of quetiapine on the possible cognitive impairment and changes of brain apoptotic regulation proteins induced by phencyclidine (PCP) in rats.
Getting beyond a prior candidate-gene approach, the present study aimed to further elucidate the molecular genetic architecture of human brain arousal regulation by conducting genome-wide association (GWA) analyses.
Jeremy Pulvers, a molecular biologist at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, whose lab presented similar results in an earlier paper, says that the new study "provides further evidence that BRCA1 … plays a specific role in brain size regulation".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com