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Different grid and dissector sizes were determined according to each brain region using a CE value ≤0.1 to indicate sampling efficiency.
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Correlations between ADC values of each brain region used a Pearson's correlation.
Visualization of virus-infected brain regions using a GFP-illuminating flashlight enables accurate and rapid dissection for biochemical analysis.
To help map those networks, a team of researchers from MIT, Harvard, Boston University and Tufts University has now developed a way to selectively activate neurons in the awake mouse brain with light and then track the resulting activity in other brain regions, using a brain-scanning technique called functional magnetic resonance imaging (fMRI).
In this study, we estimated the ATB in brain regions using a pixel-wise approach based on the differences in estimated CBF values derived from the ARG and BFM using clinical C15O2 PET data.
SUV normalized time activity curves (TACs) were generated and 11C-BUP binding potential [BPND, i.e. the ratio of the total receptor density (Bmax) on the equilibrium dissociation constant (KD)] were modeled in different brain regions using a simplified reference tissue model with cerebellum as reference region.
Carefully, the neurosurgeon places the electrodes in the desired brain regions using a set of coordinates determined by an image of the patient's brain.
However, most clustering approaches have clustered over brain regions, using a parcellation of the cortex in a number of fixed regions, making the spatial resolution of these methods limited to a regional scale.
We corrected for multiple testing across the eight brain regions using a Bonferroni correction.
Protein levels were compared between genotypes, sexes, and brain regions using a three-level mixed effects model and the Benjamini-Hochberg correction for multiple testing.
Recognizing that other variables could influence the association between metabolite levels and blood lead, the impact of covariates on this relationship were also examined by analyzing the bivariate relationship of the potential covariate with mean childhood blood lead level in each of the sampled brain regions, using a linear regression.
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