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The whole brain rate of volume loss was 2.0% per year with a greater rate of left hemisphere atrophy (2.3%/year) than right hemisphere (1.6%/year).
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Table 3 presents the difference in whole brain atrophy rate and hippocampal atrophy rate between subjects treated with placebo and those treated with galantamine.
Furthermore, we calculated age and sex-adjusted mean differences (95% CI) in total brain atrophy rate and hippocampal atrophy rate between APOE ϵ4 carriers and APOE ϵ4 noncarriers.
Third, brain atrophy rate came before hippocampal atrophy rate, which is at odds with the findings of MRI regional atrophy rate studies (e.g. Scahill et al., 2002).
In the amyloid+ group (Fig. 1B), brain atrophy rate was ordered before hippocampal atrophy rate, but the ordering was weaker than the whole population.
This was suggested to be secondary to decreased brain metabolism rate in patients under GA, as estimated by CSF production rate found lower than in conscious patients.
The mean whole brain atrophy rate was 0.52% per year and the mean hippocampal atrophy rate was 1.74% per year.
Presence of diabetes was associated with higher whole brain atrophy rate (β, 0.25% (95% CI, 0.05 to 0.49%)), but not with hippocampal atrophy rate.
In the brain the rate is much lower, but the information can be handled on millions of channels in parallel.
The neurologic scales, the brain infarct rate, and the Evans blue (EB) contents of the brains were detected.
Mean brain cooling rate was significantly greater with -7°C as compared with room temperature air in both species.
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