Sentence examples for brain progression from inspiring English sources

CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; TTbrainP, time to brain progression.

The mean PFS in the brain, calculated from the date of WBRT to the date of brain progression, was 7.4 months (range: 1-18).

The median survival time from the start of WBRT was 18 months [range, 2-65] and the median interval to brain progression was 10.5 months [range, 2-27].

Especially in regard to cerebral metastases, previous studies have confirmed the correlation between brain progression and histological features [ 30, 31], raising again the question of a possible benefit through prophylactic cranial irradiation (PCI).

In patients with HER2-positive disease, several retrospective or post hoc analyses showed a longer brain progression-free survival with trastuzumab in combination with or followed by other anti-HER2 drugs (such as pertuzumab, lapatinib, and T-DM1).

In this report, KPS and trastuzumab were associated with better overall survival, with a trend towards longer time to in-brain progression.

In an allograft model of brain tumor progression, ablation of NG2 causes a several-fold reduction in tumor progression due to deficits in pericyte/endothelial cell interactions that lead to poor vascular function.

Gefitinib ('Iressa', ZD1839) 250 mg day−1 was used to treat two patients with evidence of brain disease progression and two patients with asymptomatic BM and progressive disease in the extracranial sites.

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In this brain region, progression of brain maturation during adolescence appears to be very region-specific.

These observations, along with the fact that PDGF-Rα and -Rβ are expressed in astrocytomas [21] and glioma endothelial cells [22] point to PDGF-C as a potentially important mediator of brain tumor progression.