Future studies with microglia and mixed astrocytes/microglia cultures from the adult brain are needed to determine whether microglia can fully recapitulate the altered cytokine profile observed in the brain after LPS injection, or whether astrocytes may be involved as well.
Therefore, whether activation of VRAC helps survival or imposes further damage to neurons in the stroke brain needs to be determined.
Even though several small clinical trials have found that consuming high doses of flavanols can relax blood vessels and stimulate blood flow to the brain, more evidence is needed to determine whether they actually protect against heart attack and stroke.
Further experiments involving isolation of individual cell populations of the brain or retina will be needed to determine the specificity of these DHSs.
Further studies are needed to determine which brain parcellation strategy or spatial scale is more appropriate for the characterization of network topology in PMNE.
Further study is needed to determine whether whole brain irradiation is necessary and what dose is optimal.
First, the researchers needed to determine how a healthy brain would respond to the episode, so they recruited 12 volunteers to watch the clip inside an fMRI scanner.
A large multicentre trial will be needed to determine if stable, severely brain injured patients who meet respiratory and airway control criteria for extubation need to remain intubated.
While more research is needed to determine if multitasking is physically damaging the brain (versus existing brain damage that predisposes people to multitask), it's clear that multitasking has negative effects.
