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Few neuroimaging studies have explored brain morphometry in patients affected by chronic migraine (CM).
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Therefore, the aim of this study was to investigate the brain morphometry in a group of de novo patients diagnosed with CM, i.e. those without a previous history of medication overuse, drug withdrawal, WM abnormalities, and migraine auras, and compare it with the morphometry in healthy controls (HCs).
The ability to study changes in brain morphometry in longitudinal studies majorly depends on the accuracy and reproducibility of the brain tissue quantification.
The present study examined associations between normative drinking (alcohol initiation, binge drinking, intoxication) and brain morphometry in a sample of 96 adolescent monozygotic twins.
On the other hand, substantial evidence has accumulated that genetic factors account for the majority of differences in brain morphometry in adolescents [48].
Two initial studies using whole-brain voxel-based morphometry in patients with gambling disorder failed to identify any regions showing significant gray matter change.
Structural imaging evaluation of normalized atrophy (SIENAX) and voxel-based morphometry (VBM) were used to assess differences in global and local brain regions in patients with heterogeneous body onset and subgroups with different side of limb-onset.
Voxel-based morphometry (VBM) and surface-based morphometry (SBM) are advantageous for evaluating structural alterations (such as gray matter volume, cortical thickness and gyrification index [GI]) of the gray matter due to their ability to localize abnormal brain regions in patients without a priori hypothesis [10 12].
Here, we performed magnetic resonance imaging (MRI) voxel-based morphometry (VBM) analyses to investigate the gray matter (GM) volume of the whole brain in patients affected by CM.
Here, we performed voxel-based morphometry (VBM) analysis to investigate the grey matter (GM) density of the whole brain in patients affected by CM without medication overuse.
Brain morphometry has been used to investigate both general and regional gray matter density changes in CLBP patients.
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