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We analyzed brain morphology with a 1.5T MRI and a dedicated protocol for epilepsy.
By 27 hpf, abnormal brain morphology with a dorsally expanded hindbrain was observed in embryos injected with RNA encoding the truncated forms of Tuberin (Fig. 3K,L) but not in those injected with wild-type tsc2 RNA (Fig. 3J).
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Analysis of 2-week-old (p14) mMGS-9ANestin animals showed a dramatic alteration in brain morphology with clear signs of spongiosis and robust neuronal PAS staining (Fig 4A).
The kif22 RNAi phenotype was very similar to that seen with the antisense MO, including abnormal brain morphology and a bent tail (Fig. 7E).
Evidence for a genetic contribution to change with age includes heritability of brain morphology changes over a four-year follow up in older males (Pfefferbaum et al. 2004).
As well known [ 22] during surgery volumetric deformations occur and brain morphology changes through a dynamic process called brain shift.
Using major depressive disorder (MDD) as a disease model, we examined the feasibility of studying brain morphology and associations with remission using clinical and MRI data exclusively drawn from the EMR.
In addition, reproductive endpoints and brain morphology are preserved with CR.
We demonstrate for the first time that brain morphology varies during the menstrual cycle, with a (grey matter) volume peak at time of ovulation which can be estimated to be ∼13,5 ml for a "standard" brain.
While the associations with a priori hypothesized regions were small, larger effects were found that were widespread and suggested a more global association with brain morphology.
While there is a substantial evidence showing altered brain morphology in groups of individuals with schizophrenia, there is a little evidence to link these features with altered dermatoglyphic variables within subjects [ 7].
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