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In this study, we applied recent advances in MRI techniques to study brain microstructural alterations in early relapsing-remitting MS (RRMS) patients with minor deficits.
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To determine the pattern of brain microstructural alterations induced by chronic T. gondii infection in a murine model, in vivo noninvasive MRI was performed at high magnetic field (9.4 T).
Recent neuroimaging studies have revealed subtle microstructural alterations in the brains of patients with migraine in areas associated with the ictal-interictal cycle.
In the current investigation, we found white matter microstructural alterations in cluster headache measuring diffusion in the brain with high angular resolution.
DTI indicated altered white matter integrity in CC and microstructural alterations in caudate.
Microstructural alterations in the white matter of younger obese individuals (11, 29) may precede brain atrophy (7, 30, 31), cognitive impairment (11, 14, 32), or both in advanced metabolic syndrome.
Migraineurs exhibited several microstructural alterations in previous DTI studies [18 21].
Previous studies in primary headache disorders showed microstructural alterations in the white matter as measured by diffusion imaging.
Hence, in this study we aimed to investigate the white matter microstructural alterations in CH as described with various parameters estimated from high gradient direction diffusion MRI data.
The in vivo analysis of microstructural alterations in cluster headache provides important features of the disease, which might offer a deeper insight into the pathomechanism of the disease.
An exact overlay of such functional mapping with high-resolution images of the retina would reveal the functional impact of microstructural alterations in vivo.
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