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Patients after neurotrauma, intracranial hemorrhage, stroke, intracranial surgery, and other structural brain lesions were also excluded.
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Additionally, the number of brain lesions is also an important prognostic factor.
Three control brains of patients (sex/age/weight: ♂/33/1440 g, ♀/43/1510 g, and ♂/56/1400 g) with no history of neurologic disorder or brain lesion were also taken for the study.
The normal brain tissues distant from the lesions were also obtained from three non-astrocytoma patients who underwent brain surgery as normal controls in this study.
Few T cell clones identified in primary lesions were also found in brain metastases, and vice versa (mean Morisita Index 0.23, 95% CI 0.15 0.31; Fig. 1).
These clinical findings are supported by the results from the MRI analysis, in which the proportion of patients free from new or enlarging brain T2 lesions was also higher in the PLP10 group than the placebo group.
Brain lesions were evaluated using MRI.
Brain lesions were recorded following a pre-established checklist.
On the contrary, sparing hippocampus is feasible when brain lesions are in other regions, also if close to critical structures far from hippocampus.
Her work on brain damage and alexia, the loss of the ability to read because of brain lesions, was often cited by others in the field.
Histopathology findings closely aligned with gross findings; lesions in the brain were also histologically detected.
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