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Patients presenting with lung and/or liver and/or brain involvement were classified as having visceral metastases.
In addition to the heart, clinical/radiological signs of brain involvement were clearly present in several MTO1 mutant patients.
Magnetic resonance imaging (MRI) of the brain was performed only when clinical signs and symptoms suspicious for brain involvement were present.
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Brain involvement is usually associated with a poor prognosis [ 1– 3].
Brain involvement is a serious complication of HIV infection.
Brain involvement was associated with a moderatly increase of tumor marker CA125.
Radiologically, brain involvement is often multiple and presents a mixed, solid-cystic form [ 9].
Despite this, brain involvement is often an unrecognized complication in sepsis patients.
Brain involvement was present in 24% with HR+/HER2+ tumors and in 18% of patients with HR-/HER2+ tumors.
Most previous histopathological reports of NCM have suggested that brain involvement is secondary to overlying and invasive leptomeningeal disease [ 16].
Symptomatic presentation with bilateral renal lesions and simultaneous jejunal metastasis of choriocarcinoma without chest and brain involvement is rare and we could not find any report of such a presentation in the English literature.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com