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Brain involvement is a serious complication of HIV infection.
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Despite this, brain involvement is often an unrecognized complication in sepsis patients.
Brain involvement is usually associated with a poor prognosis [ 1– 3].
Radiologically, brain involvement is often multiple and presents a mixed, solid-cystic form [ 9].
Symptomatic presentation with bilateral renal lesions and simultaneous jejunal metastasis of choriocarcinoma without chest and brain involvement is rare and we could not find any report of such a presentation in the English literature.
Most previous histopathological reports of NCM have suggested that brain involvement is secondary to overlying and invasive leptomeningeal disease [ 16].
Brain involvement is also more common in HER2-positive tumors, but in these cases – unlike TN tumors – the specific (anti-HER2) therapies available to control the other metastatic sites allow for longer survival [ 22].
In addition, brain involvement is likely too cryptic or not easily detected in humans with CT; thus, the underlying mechanism behind the pathogenesis and sequelae of subtle BI in CT has remained largely unclear.
Brain involvement was associated with a moderatly increase of tumor marker CA125.
Patients presenting with lung and/or liver and/or brain involvement were classified as having visceral metastases.
Brain involvement was present in 24% with HR+/HER2+ tumors and in 18% of patients with HR-/HER2+ tumors.
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