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MP diagnosis should not be missed due to its aggressive behavior with brain invasion, local recurrence and metastases.
Histopathological study of completely resected meningiomas showed that loss of architecture, frequent mitotic figures, a high cellularity, increased nucleo-cytoplasmic ratio, a prominent nucleolus, brain invasion, and necrosis were correlated with the grade of the meningiomas.
Brain invasion was confidently ascertained by pathology examination.
Brain invasion is known to be correlated with a high risk of recurrence and aggressive meningioma behavior [9].
Taken all together, infiltrative phenotypes and brain invasion can be observed in about 20% of cases, and makes surgery very difficult.
Of note, the VR spaces which appear as the main anatomical site involved, radiologically, during cerebral cryptococcosis are also the site of brain invasion associated with fungemia in a relevant murine model of disseminated cryptococcosis [48] [50].
Similar(27)
53 In breast cancer, routes of extravascular fluid flux correspond to invasive fronts in mouse models of carcinoma, 51 and brain cancer invasion tightly corresponds to pathways of fluid drainage.
Invasive image pattern indicates brain abscess, invasion of tissue.
The brain slice invasion assay was performed as described previously (Valster et al, 2005).
We hypothesised that factors associated with EMT might also govern brain tumour invasion.
The pattern of findings may reflect vulnerability of these regions to initial brain viral invasion and neuroinflammation.
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