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With Dr. Ivan F. Diamond, a neurologist, and others, Dr. Schmid looked at ways to prevent bilirubin from passing into the brain in cases of child jaundice, an event that can cause brain damage.
In the inflamed brain, in cases of multiple sclerosis in humans and experimental autoimmune encephalomyelitis (EAE) in mice, however, the amount of MVs increases dramatically depending on disease severity and the extent of microglia activation [ 148].
There are two major sources for discovery of protein biomarkers - body fluids such as cerebrospinal fluid (CSF) and serum or the primary site of disease, which is the brain in cases of neurodegenerative diseases and neuroinfections.
The aim of our study was to identify differentially expressed proteins in human brain in cases of encephalitic rabies and paralytic rabies as compared to uninfected control human brain tissues by quantitative proteomics.
On the other hand post-mortem investigations of the brain in cases of cognition in schizophrenia have shown a significant correlation between NR-1 mRNA loss and cognitive deterioration [158].
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These brain areas are supplied by the basal artery and may have poorer collateral circulation than the neo-cortex, and thus represent more vulnerable areas of the brain in case of large arterial air embolism.
Whereas this strategy may work well in tumours outside the brain, in case of GBM normalisation of the tumour vascular bed and reduction of interstitial pressure comes at the expense of restored functionality of the BBB as evidenced by the reduced permeability for Gd-DTPA.
The neurostimulator contains a small battery and a computer chip that is programmed to send electrical current to the brain in case of seizures in order to disrupt it.
Voxel-based morphometry (VBM) has previously been used to evaluate brain volume in cases of bacterial meningitis [ 8, 9], as it can help evaluate anatomic brain abnormalities in varying subgroups.
Hallucinatory experiences can be brought about through direct stimulation of the exposed brain, as in cases of local cortical arousal under the neurosurgeon's stimulating electrode.
Proinflammatory cytokines have been implicated in the mechanisms that are responsible for brain injury in cases of intrauterine infection.
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