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Abnormal insulin signaling in the brain has been associated with Alzheimer disease.
In addition, the expression of miR-206 in the brain has been associated with schizophrenia [24].
Increased N-AChE expression in the AD brain has been associated with disease progression and apoptotic cell death [62].
Mitochondria are the chief source of ROS within the cell, and age-related oxidative damage in the brain has been associated with neurodegenerative diseases such as Alzheimer's and Parkinson's diseases [15].
A shift towards an increased proportion of the longer, highly fibrillogenic and neurotoxic Aβ species (i.e., Aβ42) in the brain has been associated with the neurodegeneration leading to AD. Blocking Aβ production can be a therapeutic target.
The remarkable degree of inter- and intra-species variation in the distribution of V1aR in the brain has been associated with variation in social behavior [ 2- 5].
Similar(52)
Structural alterations of brain have been associated with the risk-taking of ASD youngsters, even among those merely vulnerable to ASD through family history.
Interestingly these regions of the brain have been associated with pathophysiological hyperexcitability; disruption of K+ currents in the dentate gyrus can lead to abnormal hippocampal synchronization and temporal lobe seizures [9].
Active transposable elements in the brain have been associated with aging and neuronal decline (Coufal et al. 2009; Li et al. 2013).
Epigenetic changes in the brain have been associated with a range of biological and cognitive processes including neurogenesis (10), brain growth and development (11), learning and memory (12), drug addiction (13), neurodegeneration (14) and circadian rhythm (15).
Systemic inflammation is likely to be the common factor linking the two diseases; acute and chronic effects of inflammation in the brain have been associated with cognitive decline and risk of dementia in older adults [ 34].
More suggestions(17)
encephalitis has been associated
brain has been conditioned
brain has been softened
brain has been altered
brain has been created
brain has been replaced
brain has been shown
brain has been shaped
brain has been riddled
brain has been impacted
brain has been spurred
brain has been shorted
brain has been neglected
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brain has been shot
brain has been numbed
brain has been rewired
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