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He predicted that other brain genes would be found to have changed in other populations.
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Rather less than more DE genes would be expected to overlap with the selected genes in the brain correlating with the combination MCT8/THRA2.
We hypothesized that paper wasp brain gene expression patterns would be related to gene expression associated with caste, exposure to queen pheromone and/or aggression in honey bee workers.
"If you get a gene linked to autism, for instance, you'd want to look at that same gene for schizophrenia; if it's a social brain gene, then it would be expected to have opposite effects on these disorders, whether gene expression was turned up or turned down".
We further hypothesized that such alterations in behavior, and the associated modifications in brain gene expression profiles, would be transmitted to the offspring, thereby suggestively prepare the offspring for the parental environment.
"Brain training" would be an easy fix.
Although we are particularly interested in the large number of fat-expressed genes that were identified in this and earlier screens [ 12, 22], we also note that several of the identified transcripts are expressed in brains as would be expected for genes that function in behavior.
Anybody with a brain would be suspicious.
We hypothesized that brain gene expression profiles after traumatic brain injury and hemorrhagic shock would be modulated by FFP resuscitation.
But the gene activity levels in the human brain were strikingly different from those in the chimp, suggesting that the rate of evolution of human brain genes has been five times faster than that of the chimp brain genes.
My day job would be brain surgeon.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com