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The results of these comparisons suggest that V+ bees display a brain gene expression profile associated with heightened arousal.
We also compared the brain gene expression profile of V+ bees to bees exposed to brood pheromone [8], which is not known to affect arousal.
We hypothesised that each position or rank within a group has a distinctive brain gene expression profile that correlates with behavioural phenotype.
To explore this idea, we compared the brain gene expression profile of V+ bees with genomic profiles from another study that were induced by perception of pheromone signals (causing arousal in receivers).
Compelling evidence that the NVU is probably important in HAND without HIVE was obtained from a recently reported brain gene expression profile [ 21].
We also determined whether Nosema and Varroa modified the brain gene expression profile in a manner consistent with some previously characterized behavioral phenotypes or in a completely different way.
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We hypothesized that brain gene expression profiles after traumatic brain injury and hemorrhagic shock would be modulated by FFP resuscitation.
We thus examined the correlation between cerebral cortical DOC levels and whole brain gene expression profiles across the BXD strains.
We further hypothesized that such alterations in behavior, and the associated modifications in brain gene expression profiles, would be transmitted to the offspring, thereby suggestively prepare the offspring for the parental environment.
The rank correlation coefficient among different tissues showed that homologous tissues in three different species are more similar compared to non-homologous tissues (Figure 5); especially brain tissues are highly correlated within the three species indicating evolutionary constraints are posed on brain gene expression profiles.
Global brain gene expression profiles from mice 145 days post-inoculation, with either mock inoculum or the RML prion strain, were compared applying a 1.3-fold change as the lower limit, lower 90% confidence boundary of fold change and p values of <0.05.
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