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Brain gene array data suggest that the neurovascular unit is a critical target in virally suppressed patients with HAND.
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Here, using gene array data in the human postmortem brain of control subjects [10] (n = 14), we demonstrate that a large number of genes displayed positive correlations of transcript levels between amygdala and cingulate (Figure 1A D), resulting in a unimodal distribution (Median r = 0.32) (Figure 1E).
All the gene array data has been deposited in the GEO database (GSE22054).
Gene array data was validated by qRT-PCR using Taqman Assay-On-Demand oligonucleotides for the following genes (Table 6).
Functional analysis of gene array data set.
DS contributed to the analysis of gene array data.
Full gene array data were submitted to gene expression omnibus (GEO Accession #: GSE46471).
Our gene array data are available from the Gene Expression Omnibus web repository, accession number GSE26308.
Gene array data were deposited in the Gene Expression Omnibus database, accession number GSE37567 [ 85].
Gene array data analysis.
The gene array data have been deposited in the Gene Expression Omnibus, accession number GSE38457.
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