To accomplish this we are utilizing novel proteomic, genome engineering, and neural circuit approaches that we have developed to functionally link how perturbations to neural proteomes alter brain function relevant to neurodevelopment and psychiatric disorders.
Several of these deregulated miRNAs overlap with those found in human AD studies and potentially affect important biological pathways essential for proper brain function relevant to AD. miRNAs seem to provide essential neuroprotective functions, as decreases result in neurodegeneration [36], [37], [38].
New mutant mouse models allow gene-based manipulation of brain function relevant to sequential patterns, but no current animal model of spontaneous OCD-like behaviors has so far been reported to exhibit sequential super-stereotypy in the sense of a whole complex serial pattern that becomes stronger and excessively rigid.
Our functional enrichment test of these 47 genes suggested that this ranking algorithm identifies gene sets with coherent biological functions relevant to brain responses to ethanol and neural adaptations occurring with alcoholism.
Akin to the primary auditory cortex that resides in HG, the posterior STP also has structural leftward asymmetry [ 57, 58], which indicates a relationship between this brain region and the leftward lateralized specific functions relevant to speech perception.
Astrocytes have many functions relevant to motor neuron physiology.
In order to explore the gene function relevant to the brain metastasis of lung cancer, GO analysis was conducted to group these differentially expressed genes into signaling pathways.
Alterations in brain function become relevant to human conditions when translated into altered patterns of behavior.
dunce-like optomotor phenotypes in D0264, D0067, and D0177 suggest that these mutations might compromise brain circuits relevant to dunce function (i.e., they may represent downstream plasticity genes expressed in the same cells as dunce).
The developing brain functions according to unique processing rules.
