Sentence examples for brain function and pathology from inspiring English sources

There is widespread recognition that reactive oxygen species (ROS) play key roles in normal brain function and pathology in the context of neurological disease.

As one of the indispensable important metal ions in metabolic processes, Fe3+ plays an essential and crucial role in a variety of biological processes such as brain function and pathology, gene transcription, immune function, and mammalian reproduction [1 9].

It has emerged that IFN-I and downstream genes are readily induced in the brain (Cunningham et al., 2007; Wang et al., 2008) and have multiple effects on brain function and pathology (Owens et al., 2014).

Well-designed cohort studies, convergent evidence from appropriate laboratory models, and long-term clinical trials using surrogate biomarkers of brain function and neural pathology could provide relevant answers.

Using this approach we have identified novel and robust DMRs associated with >400 coding transcripts, many of which have known roles in brain function and AD pathology.

A broad variety of implantable electrical and chemical recording devices have made innumerable and seminal contributions to our current understanding of normal brain function and the pathology of brain disorders and injuries.

Several recent observations point to an important role of these factors in proper brain function and its pathologies.

For the same reason, chronic impairments of neuronal metabolism would be expected to compromise brain function and contribute to brain pathology, which may be the case in epilepsy (due to runaway excitatory activity or directly to metabolic disorders [57]), sepsis [58], mitochondrial disorders, which strongly affect the brain [59], and Alzheimer's disease [60].

Microelectrode recording arrays of 60 100 electrodes are commonly used to record neuronal biopotentials, and these have aided our understanding of brain function, development and pathology.

8,63,64 We hypothesize that the axonal and synaptic pathology shown here constitute key factors contributing to the overall frailty of brain function and may underpin the failure of the degenerating brain to demonstrate resilience upon "stress-testing" with systemic inflammation.

The characteristic surface morphology of the mammalian brain is closely correlated with brain function and dysfunction.