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PET is a specific imaging technique applying in researches of brain function and neurochemistry of small animals, medium-sized animals, and human subjects [46, 47, 48].
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The characteristic surface morphology of the mammalian brain is closely correlated with brain function and dysfunction.
Micro-MRI is a non-invasive imaging tool for monitoring brain anatomy, function, and neurochemistry over time in the same animal [11].
Recent progress has provided evidence that psychiatric disorders are brain disorders characterized by abnormalities in the structure, function and neurochemistry in distributed neural networks [ 8].
Neuroimaging research in patients with chronic pain have revealed altered structure, function, and neurochemistry in the frontal-limbic-brainstem regions compared with healthy controls underscoring the importance of this descending neuro-circuit for the regulation of pain in humans.
Linking neurochemistry and brain function requires an understanding of the cell−cell signaling peptides (SPs) used in the brain.
Giovanoli et al. examined these happenings in a mouse model and found out that they induce "synergistic pathological effects on adult behavioral functions and neurochemistry" [27].
Early-life adversity and epigenetic mechanisms might explain some of the link between suicide risk and brain circuitry and neurochemistry abnormalities.
Findings from brain imagining and neurochemistry studies support the behavioral findings.
Moreover, several investigators have reported ongoing transient and dynamic changes in brain metabolism and neurochemistry after brain injury [ 7, 8].
Studying differences in brain morphology and neurochemistry between strains with innate differences for alcohol-related traits allows for greater insight into biological factors promoting AUDs.
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