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The institute, started in 2003 with $100 million in seed money from Microsoft co-founder Paul Allen, hopes the atlas will become a valuable resource for scientists studying brain function and disease.
The role of cholinergic and catecholaminergic (dopaminergic, noradrenergic, and adrenergic) neurotransmission in brain function and disease has been an object of long-standing scientific interest, and, as a result, the anatomy of the cholinergic and catecholaminergic systems has been intensively studied in both normal and diseased brains in a wide variety of species.
In addition, the ability to play back balanced, yet random, patterns of excitation and inhibition may open up new horizons into understanding the causal role of precise spike timing or neural synchrony in brain function and disease, an area of longstanding yet growing interest.
The biological basis for sex differences in brain function and disease susceptibility is poorly understood.
Additional investigations are necessary to corroborate these findings, and to determine their relevance for normal brain function and disease.
Although potentially providing a novel genetic link between obesity and brain structure, the relevance of these findings for normal brain function and disease remains to be determined.
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Thousands of lncRNAs have been recently discovered in a wide range of mammalian systems, related to development, epigenetics, cancer, brain function and hereditary disease.
This review gives an overview of modern network theory and its applications to healthy brain function and neurological disease, in particular using techniques from clinical neurophysiology, such as EEG and MEG.
Evidence is accruing that the EBJC plays a central role in brain function and neurological disease.
Prenatal stress has been related to several diseases related to brain function and chronic degenerative diseases (Davis et al, 2011; Harris and Seckl, 2011).
Damage to WM alters brain function, and numerous neurological diseases feature WM involvement.
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