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When agitation accompanies brain failure in a critical care setting, a failure to integrate cerebral functioning exists, and this constitutes a true emergency.
Adjuvant WBRT was found to decrease the distant brain failure in SRS-treated patients from 64% to 17% after 6 months [ 99].
Integrative brain failure in the ICU environment is almost always associated with a hemodynamic or metabolic decompensation, either intra-or extracranial.
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To determine the incidence, risk factors and outcomes of acute brain failure (ABF) in a mixed medical and surgical cohort of critically ill patients and its effect on ICU & hospital mortality.
To determine if temozolomide reduces the risk of distant brain failure (DBF, metachronous brain metastases) in patients with 1 to 4 brain metastases treated with radiosurgery without whole-brain radiation therapy (WBRT).
Short-term hypoglycemia has been suggested to cause brain fuel deprivation that, if unchecked, results in functional brain failure that is typically corrected after the plasma glucose concentration is raised (27).
In addition to being a potential "second hit" for psychosis in a vulnerable brain, failure to control for this confounding variable could underlie the inconsistent findings in previous DTI studies of early phase schizophrenia and would demand for this variable to be factored into future studies of white matter abnormalities in psychosis.
Another, related problem for the sufficiency of total brain failure for human death arises from reflection on locked-in syndrome.
2. Safar et al. Resuscitation after Brain Ischemia, in Grenvik A and Safar P Eds: Brain Failure and Resuscitation, Churchill Livingstone, New York, 1981; 19811981
Delirium, or acute brain failure, often has organic causes.
First, in the case of at least some members of our species, total brain failure is not necessary for death.
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