Specifically, a major goal in the study of neuropsychiatric disorders has been to identify underlying mechanisms of brain dysfunction with the expectation that these insights may allow a better diagnosis, prevention and effective treatments for these disorders.
Delirium is a common form of acute brain dysfunction with prognostic significance.
With regard to acute brain dysfunction, is the delirium-to-coma transition merely a continuum of progressively lesser degrees of arousal, or is there a fundamental change in the pathophysiology of the acute brain dysfunction with this transition?
An age cut-off value of 57 years determined brain dysfunction with sensitivity 83% and specificity 63%.
Progressive brain changes might occur after the first psychotic/depressive episode, resulting in the inadequate maturation of the cortex [ 101- 108] and provoking mild but progressive brain dysfunction with cognitive impairments in participants with bipolar disorder [ 103, 109- 112].
To identify infectious etiologies of encephalitis in Thailand, we conducted surveillance in 7 hospitals during July 2003 August 2005 and selected patients with acute onset of brain dysfunction with fever or hypothermia and with abnormalities seen on neuroimages or electroencephalograms or with cerebrospinal fluid pleocytosis.
Although no-one in the field of synaptic plasticity, or in the field of brain dysfunction with aging, would deny the importance of membrane lipids, particularly of cholesterol, for either of these processes, relevant information is scarce if not completely lacking.
Is developmental dyscalculia a unique pathophysiology that involves abnormalities restricted to the intraparietal sulcus or is it due to multiple brain dysfunctions with multiple cognitive deficits [ 24]?
Diagnosing brain dysfunction in a patient with sepsis implies a systematic diagnostic approach of all potential factors, in addition to sepsis, that can contribute to aggravate or prolong brain dysfunction.
