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A strong expression starting at 36 h post fertilization (hpf) was observed by real-time PCR and could be detected in brain by in situ hybridization, suggesting that TRIM3a protein might play an important role in brain development in zebrafish.
Pax2 and pax6a, members of the paired box family of transcription factors are important for the brain development in zebrafish.
In view of the unique tissue expression profile of PRL2 in zebrafish, we have also examined the possible involvement of zfPRL2 on eye and brain development in zebrafish.
We found that BPA exposure influences DV patterning, somite formation, and brain development in zebrafish embryos.
SUMMARY: The paracrine activity of Engrailed, together with its PBX-interacting hexapeptide motif, is involved in boundary formation during brain development in zebrafish.
Three stages (60 75% epiboly, 8 10 somite, and prim-5) were selected for in situ screening of different molecular markers, whereas BPA exposure altered early dorsoventral (DV) patterning, segmentation, and brain development in zebrafish embryos within 24 hours of exposure.
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This is consistent with a notion that the amphetamines can recapitulate developmental processes in the brain [73] since amphetamine conditioned place preference is associated with enrichment of transcription factors that regulate brain development in the zebrafish [74].
To assess potential differences in zebrafish brain development in response to cocaine, we have used α1-T-GFP transgenic zebrafish, with a GFP reporter driven by the 1.696-kb 1.696-kb α1-tubulin promoter fragoldfish2].
THE LEARNING BRAIN Memory and Brain Development in Children.
These results suggest that nestin is required for normal brain and eye development in zebrafish.
Visual dysfunction in CLN6 NCL may also be related to Zip7 expression changes, as Zip7 plays a role in brain and eye development in zebrafish [ 63].
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