Sentence examples for brain development in vitro from inspiring English sources

As a model of neural development, we employed primary fetal human neural progenitor cells (hNPCs), which are cultured as neurospheres and mimic basic processes of brain development in vitro: proliferation, migration, and differentiation.

We investigated the effects of these PBDEs on the developmental neurotoxicity (DNT)–specific end points proliferation, migration, and differentiation, as well as cell viability, in a human model that mimics brain development in vitro (Fritsche et al. 2005; Moors et al. 2007, 2009, 2010).

Our initial goal was to investigate the mechanisms leading to disturbance of human brain development in a human in vitro model.

We studied the effects of AhR ligands on basic processes of brain development in two comparative in vitro systems to determine whether AhR-activation is the underlying mechanism for reported DNT of POPs in humans.

Previous studies showed that there is a significant increase in editing levels of protein-coding regions during brain development and in-vitro neural differentiation [31], [32], [33].

We used module preservation analysis [ 40] to compare the identified modules with independent expression profiles from in vivo human brain development and in vitro neuronal differentiation of primary human neural progenitor cells (phNPCs) (Methods).

These experiments showed that all of the tested genes were indeed induced during brain development and in vitro neuronal differentiation (Fig. 6).

Since interaction of the SIL1 mutants with HSPA5 was significantly diminished in vitro (Fig  2B), the SIL1-HSPA5 interaction may be essential for cortical neuron migration and the impaired interaction may account for abnormal brain development in MSS.

THE LEARNING BRAIN Memory and Brain Development in Children.

"They are different in hormonal development, in brain development, in physiological development and in social development," they say.

In this report we focused on the several processes involved in brain development and identified in vitro and nonmammalian tests that may allow the generation of data sets that can help identify DNT hazards.