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In order to develop a genetic model in which the effects of FMRP on brain development can be easily studied during development we screened for knock-out alleles in the zebrafish system.
At its extremes, brain development can be sufficiently abnormal as to lead to personality disorders," he said.
The disturbance in brain development can be caused either by genetic factors or by external factors, such as prenatal exposure to influenza virus, birth complications, etc.
I explain how brain development can be severely affected in children who have been exposed to repetitive trauma in their early years, and how children who have not had their needs met as babies can develop insecure attachment styles.
This ability of the brain to reorganize its network of neurons is called "neuroplasticity". Studies recently published in Cognitive Processing show that brain development can be enhanced -- not only during adolescence but at any age -- through the practice of meditation, and that different meditation techniques have different effects on the brain.
The present results show that for the rat dentate gyrus, the sensitive time window during which brain development can be affected, appears to extend at least into the early postnatal period.
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When a child is deprived of the right nutrition early on in life, his physical development and brain growth can be irreversibly damaged.
The developing fetus and young children are disproportionately affected by methyl mercury exposure, because many aspects of development, particularly brain maturation, can be disturbed by the presence of methyl mercury.
Normal and abnormal microstructural brain development can also be studied using DWI based on the differential diffusion properties of the various tissues (FA scalars and tractography).
The three-dimensional models and sophisticated software facilitate the analysis and visualisation of morphological changes and gene expression patterns during early brain development and can be applied to the development of other complex structures.
Perhaps equally valuable, we showed how many features of developmental neurotoxicity are shared by an organochlorine (dieldrin) and a metal (Ni2+), thus leading to a number of predictions about the effects of these agents on brain development that can be tested in vivo.
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