Understanding the role that MeCP2 plays in brain development and maturation is important for understanding the pathogenesis of these disorders and identifying potential therapeutic targets.
Mapping these indices over the whole brain on clinical scanners presents new opportunities for understanding brain development and disorders.
Determining the functions of NRs will provide ample opportunities for better understanding brain development and neuron degeneration.
Even so, it could revolutionise both our understanding of brain development and the design of drug treatments.
"There's a growing understanding of brain development and the fact that children are significantly influenced in their homes long before they get to school," said Sarah Walzer, the national director of the program, who is based in Garden City.
During the past decade, substantial progress has been made in our understanding of brain development and the genetic basis of MCPH.
These findings advance a new understanding of healthy brain development and provide a foundation from which to assess atypical development.
In addition, study of these disorders contributes greatly to the understanding of normal brain development and its perturbations.
Cell culture of human-derived neural stem cells (NSCs) is a useful tool that contributes to our understanding of human brain development and allows for the development of therapies for intractable human brain disorders.
Lead investigator Prof David Edwards said: "The number of babies born prematurely is increasing, so it has never been more important to improve our understanding of how preterm birth affects brain development and causes brain damage.
