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Kanazawa T. Brain delivery of small interfering ribonucleic acid and drugs through intranasal administration with nano-sized polymer micelles.
The results suggest brain delivery of nanoceria will be a challenge.
However, transport affinity for these agents is low and brain delivery is limited.
However, their application in brain delivery is relatively a new area of research.
The nanoparticle has emerged as a potential vector for brain delivery, able to overcome the problems of current strategies.
Nanotechnology offers intriguing potential for addressing these challenges in siRNA brain delivery in conjunction with chemical and biological modification strategies.
PEGylated-PLGA nanoparticles of Epigallocatechin-3-gallate were designed to protect the drug and to increase the brain delivery.
Finally, the biodistribution study of CS-NLC-DiR demonstrated an efficient brain delivery of the particles after intranasal administration.
The nanoparticle has emerged as a potential vector for brain delivery, able to overcome the difficulties of modern strategies.
Niosomes can perform brain delivery, in fact polysorbates, can act as an anchor for apolipoprotein E from blood plasma.
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We also highlight current gaps in the literature and suggest how research can directly examine the assumptions of nose-to-brain delivery of psychopharmacological agents in humans.
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CEO of Professional Science Editing for Scientists @ prosciediting.com