Sentence examples for brain degradation from inspiring English sources

An insufficiency of this enzyme causes a disease known as sulfite oxidase deficiency, characterized by neurological disorders, mental retardation and brain degradation [ 45].

Clearance of Aβ from the brain takes place by three pathways, transport across the BBB, brain degradation, and bulk flow of cerebrospinal fluid.

Studies prove that children are more vulnerable to permanent brain degradation when exposed to alcohol than adults.

Neprilysin is the major protease mediating brain Aß degradation [ 39].

In vCJD (variant Creutzfeldt Jakob disease), the human counterpart of BSE (bovine spongiform encephalopathy), up to 90% of total PrP present in the brain resists degradation with thermolysin, whereas only ∼15% of this material resists digestion by PK.

The aim of the present study was to measure levels of free active MMP-2 and MMP-9 in CSF of SLE patients with CNS lupus, and to relate these data to clinical and laboratory measures of brain parenchymal degradation.

Then small molecule metabolites transported through the blood-brain barrier, the degradation of the microenvironment of the brain enhances cerebral tissue damage, which showed that the metabolites were significantly correlated with cerebral damages.

"The big implication here is that we can potentially affect brain aging and degradation, even dementia, by targeting factors in the periphery rather than having to target the brain directly".

The mechanism that is thought to have a significant influence on delayed effects involves formed blood cells and chemical mediators, which cause brain lipid peroxidation (degradation of unsaturated fatty acids).

Whereas no Rgs4 could be detected in the Ate1-containing brain (owing to degradation of Rgs4 by the N-end rule pathway [11]), an intense band of Rgs4 was present in the Ate1-deficient brain, illustrating high penetrance of Ate1 deletion in the brain (Fig. 1D).

Elimination of Aβ from the brain involves enzymic degradation, its absorption into the blood and drainage of Aβ along perivascular lymphatic drainage pathways.