This would considerably contribute to the understanding of the cellular and anatomical brain contribution to the memory deficits that are observed in the study.
We also summarize the potential functions of these newborn neurons in the adult brain, their contribution to behavior, and their relevance to disease.
However, if the radiometabolites of a PET radioligand are lipophilic enough to enter the brain, their contribution to the PET signal will preclude accurate quantitation using only parent radioligand as the input function.
Following intra-nasal delivery, low cerebral hemisphere levels of variants were obtained at 20 min, with a trend towards faster clearance of the high FcRn binder (N434A); however, the relatively higher serum levels confounded analysis of brain FcRn contribution to efflux.
Using the temporal decay data and BF ec(t 0,0), we can also estimate the brain (cerebral) contribution to the total decay rate with pressure off.
Although the biological effect of the Rep1 expansion was observed in the most relevant organ to PD expression, i.e. the brain, its contribution appeared specific because its enhancer role was not recorded in the corresponding blood specimens.
However, in highly scattering tissue such as the brain, the contribution of the ultrashort excitation pulse should be accounted for and can be modeled as a Dirac delta function [ 19, 33].
Due to the heterogeneous nature of most brain injuries, the contributions of gray and white matter involvement to motor deficits and recovery potential remain obscure.
This book easily could have been the story of one broken brain and its contributions to science, but thankfully, it is so much more.
Up to now, it is not clear which microscopical mechanisms underlie brain volume changes: contributions can be attributed to changes in vascular supply, intra- or intercellular water shifts, cell hypertrophy, synaptogenesis or even (neuro- neogenesis [6], [22], [25], [26], [27].
