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Functional brain clusters shared across groups and cognitive states (rest and auditory task) were defined.
Mike Greicius, MD, has used fMRI to differentiate among networks, composed of widely distributed brain clusters working in concert, that are active during diverse mental tasks such as singing to oneself or working on a math problem.
Seeing the object of their desire increased activity in brain clusters called the insula, cingulate, putamen, and caudate nucleus--regions, curiously enough, that also light up under cocaine-induced euphoria, Bartels says.
This contrast yielded significant brain clusters (Table 1), which were used as functional localizers.
No significant whole brain clusters were found for the comparison of all non-remitters and all remitted patients.
Main effects of group, and within-group correlations with hypermobility score, are reported for all brain clusters of ≥10 contiguous voxels with significance threshold P<0.001 uncorrected.
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Whole brain tractography, based on diffusion-weighted MRI, generates vast sets of fibers throughout the brain; clustering them into consistent and recognizable bundles can be difficult as there are wide individual variations in the trajectory and shape of WM pathways.
The occipital and temporal regions of the brain clustered by subject rather than by region (Figure 1B).
In addition, the gonad cluster grouped together with the brain cluster, indicating the similarity of the transcriptome among these organs (Fig. 4).
Each ROI was defined as an 8 mm-diameter sphere centered in the coordinates of the peak activated voxels of each activated brain cluster.
Each ROI was defined as an 8 mm-diameter sphere centered in the coordinates of the peak deactivated voxels of each deactivated brain cluster.
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